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Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase
AMP-activated protein kinase (AMPK) is a master sensor and regulator of cellular energy status. Upon metabolic stress, AMPK suppresses anabolic and promotes catabolic processes to regain energy homeostasis. Cancer cells can occasionally suppress the growth restrictive AMPK pathway by mutation of an...
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| 出版年: | Cell |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5629913/ https://ncbi.nlm.nih.gov/pubmed/25679763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.034 |
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