Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase

AMP-activated protein kinase (AMPK) is a master sensor and regulator of cellular energy status. Upon metabolic stress, AMPK suppresses anabolic and promotes catabolic processes to regain energy homeostasis. Cancer cells can occasionally suppress the growth restrictive AMPK pathway by mutation of an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell
Päätekijät: Pineda, Carlos T., Ramanathan, Saumya, Tacer, Klementina Fon, Weon, Jenny L., Potts, Malia B., Ou, Yi-Hung, White, Michael A., Potts, Patrick Ryan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5629913/
https://ncbi.nlm.nih.gov/pubmed/25679763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.01.034
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