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Specificity in the actions of the UBR1 ubiquitin ligase in the degradation of nuclear receptors()

The UBR1 ubiquitin ligase promotes degradation of proteins via the N-end rule and by another mechanism that detects a misfolded conformation. Although UBR1 was shown recently to act on protein kinases whose misfolding was promoted by inhibition of Hsp90, it was unknown whether this ubiquitin ligase...

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Bibliografiset tiedot
Päätekijät: Sultana, Rasheda, Theodoraki, Maria A., Caplan, Avrom J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821023/
https://ncbi.nlm.nih.gov/pubmed/24251101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2013.09.003
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