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Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation

Quality control and degradation of misfolded proteins are essential processes of all cells. The endoplasmic reticulum (ER) is the entry site of proteins into the secretory pathway in which protein folding occurs and terminally misfolded proteins are recognized and retrotranslocated across the ER mem...

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Detalhes bibliográficos
Main Authors: Stolz, Alexandra, Besser, Stefanie, Hottmann, Heike, Wolf, Dieter H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780849/
https://ncbi.nlm.nih.gov/pubmed/23988329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304928110
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