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Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation
Quality control and degradation of misfolded proteins are essential processes of all cells. The endoplasmic reticulum (ER) is the entry site of proteins into the secretory pathway in which protein folding occurs and terminally misfolded proteins are recognized and retrotranslocated across the ER mem...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780849/ https://ncbi.nlm.nih.gov/pubmed/23988329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304928110 |
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