Genome-wide identification and gene expression profiling of ubiquitin ligases for endoplasmic reticulum protein degradation

Endoplasmic reticulum (ER)-associated degradation (ERAD) is a mechanism by which unfolded proteins that accumulate in the ER are transported to the cytosol for ubiquitin–proteasome-mediated degradation. Ubiquitin ligases (E3s) are a group of enzymes responsible for substrate selectivity and ubiquiti...

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Pubblicato in:Sci Rep
Autori principali: Kaneko, Masayuki, Iwase, Ikuko, Yamasaki, Yuki, Takai, Tomoko, Wu, Yan, Kanemoto, Soshi, Matsuhisa, Koji, Asada, Rie, Okuma, Yasunobu, Watanabe, Takeshi, Imaizumi, Kazunori, Nomura, Yausyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971459/
https://ncbi.nlm.nih.gov/pubmed/27485036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30955
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