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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

Eukaryotic cells maintain proteostasis by quality control (QC) degradation. These pathways can specifically target a wide variety of distinct misfolded proteins, and so are important for management of cellular stress. Although a number of conserved QC pathways have been described in yeast, the E3 li...

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Détails bibliographiques
Auteurs principaux: Heck, Jarrod W., Cheung, Samantha K., Hampton, Randolph Y.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824284/
https://ncbi.nlm.nih.gov/pubmed/20080635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910591107
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