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Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1

Eukaryotic cells maintain proteostasis by quality control (QC) degradation. These pathways can specifically target a wide variety of distinct misfolded proteins, and so are important for management of cellular stress. Although a number of conserved QC pathways have been described in yeast, the E3 li...

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Detalhes bibliográficos
Main Authors: Heck, Jarrod W., Cheung, Samantha K., Hampton, Randolph Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824284/
https://ncbi.nlm.nih.gov/pubmed/20080635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910591107
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