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Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control

Chaperones can mediate both protein folding and degradation. This process is referred to as protein triage, which demands study to reveal mechanisms of quality control for both basic scientific and translational purposes. In yeast, many misfolded proteins undergo chaperone-dependent ubiquitination b...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Singh, Amanjot, Vashistha, Nidhi, Heck, Jarrod, Tang, Xin, Wipf, Peter, Brodsky, Jeffrey L., Hampton, Randolph Y.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927186/
https://ncbi.nlm.nih.gov/pubmed/32966159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-08-0541
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