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Oncogenic MAGEA-TRIM28 ubiquitin ligase downregulates autophagy by ubiquitinating and degrading AMPK in cancer

Autophagy is commonly altered in cancer and has a complicated, but important role in regulation of tumor growth. Autophagy is often tumor suppressive in the early stages of cancer development, but contributes to the late stages of tumor growth. Because of this, putative oncogenes that modulate autop...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Pineda, Carlos T, Potts, Patrick Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509443/
https://ncbi.nlm.nih.gov/pubmed/25945414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1034420
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