The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer

Ets related gene (ERG) is a transcription factor that is overexpressed in 40% of prostate tumors due to a gene fusion between ERG and TMPRSS2. Because ERG functions as a driver of prostate carcinogenesis, understanding the mechanisms that influence its turnover may provide new molecular handles to t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Wang, Shan, Kollipara, Rahul K., Humphries, Caroline G., Ma, Shi-Hong, Hutchinson, Ryan, Li, Rui, Siddiqui, Javed, Tomlins, Scott A., Raj, Ganesh V., Kittler, Ralf
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5323126/
https://ncbi.nlm.nih.gov/pubmed/27626314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11915
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