The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasome-mediated degradation of PPARγ

Peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-dependent transcription factor that regulates adipocyte differentiation and glucose homeostasis. The transcriptional activity of PPARγ is regulated not only by ligands but also by post-translational modifications (PTMs). In this st...

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Pubblicato in:Exp Mol Med
Autori principali: Lee, Jae Min, Choi, Sun Sil, Lee, Yo Han, Khim, Keon Woo, Yoon, Sora, Kim, Byung-gyu, Nam, Dougu, Suh, Pann-Ghill, Myung, Kyungjae, Choi, Jang Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6189217/
https://ncbi.nlm.nih.gov/pubmed/30323259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-018-0162-6
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