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Aryl hydrocarbon receptor (AhR) regulates adipocyte differentiation by assembling CRL4B ubiquitin ligase to target PPARγ for proteasomal degradation

Peroxisome proliferator-activated receptor γ (PPARγ) is the central regulator of adipogenesis, and its dysregulation is linked to obesity and metabolic diseases. Identification of the factors that regulate PPARγ expression and activity is therefore crucial for combating obesity. Aryl hydrocarbon rec...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Dou, Hao, Duan, Yuyao, Zhang, Xiaohui, Yu, Qian, Di, Qian, Song, Yu, Li, Peishan, Gong, Yaoqin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6885645/
https://ncbi.nlm.nih.gov/pubmed/31653699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009282
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