PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273

Peroxisome proliferator-activated receptor γ (PPARγ) is a master regulator of adipose tissue biology. In obesity, phosphorylation of PPARγ at Ser273 (pSer273) by cyclin-dependent kinase 5 (CDK5)/extracellular signal-regulated kinase (ERK) orchestrates diabetic gene reprogramming via dysregulation of...

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Publicado no:Cells
Main Authors: Khim, Keon Woo, Choi, Sun Sil, Jang, Hyun-Jun, Lee, Yo Han, Lee, Eujin, Hyun, Ji-Min, Eom, Hye-Jin, Yoon, Sora, Choi, Jeong-Won, Park, Tae-Eun, Nam, Dougu, Choi, Jang Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072254/
https://ncbi.nlm.nih.gov/pubmed/32024237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9020343
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