A Novel Non-agonist Peroxisome Proliferator-activated Receptor γ (PPARγ) Ligand UHC1 Blocks PPARγ Phosphorylation by Cyclin-dependent Kinase 5 (CDK5) and Improves Insulin Sensitivity

Thiazolidinedione class of anti-diabetic drugs which are known as peroxisome proliferator-activated receptor γ (PPARγ) ligands have been used to treat metabolic disorders, but thiazolidinediones can also cause several severe side effects, including congestive heart failure, fluid retention, and weig...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Choi, Sun-Sil, Kim, Eun Sun, Koh, Minseob, Lee, Soo-Jin, Lim, Donghyun, Yang, Yong Ryoul, Jang, Hyun-Jun, Seo, Kyung-ah, Min, Sang-Hyun, Lee, In Hee, Park, Seung Bum, Suh, Pann-Ghill, Choi, Jang Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176243/
https://ncbi.nlm.nih.gov/pubmed/25100724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566794
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados