The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ

Adipocyte differentiation is a strictly controlled process regulated by a series of transcriptional activators. Adipogenic signals activate early adipogenic activators and facilitate the transient formation of early enhanceosomes at target genes. These enhancer regions are subsequently inherited by...

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Pubblicato in:eLife
Autori principali: Watanabe, Masashi, Takahashi, Hidehisa, Saeki, Yasushi, Ozaki, Takashi, Itoh, Shihori, Suzuki, Masanobu, Mizushima, Wataru, Tanaka, Keiji, Hatakeyama, Shigetsugu
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2015
Soggetti:
Biochemistry
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426667/
https://ncbi.nlm.nih.gov/pubmed/25905670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05615
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