A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets

The identification of true substrates of an E3 ligase is biologically important but biochemically difficult. In recent years, several techniques for identifying substrates have been developed, but these approaches cannot exclude indirect ubiquitination or have other limitations. Here we develop an E...

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Foilsithe in:Commun Biol
Main Authors: Watanabe, Masashi, Saeki, Yasushi, Takahashi, Hidehisa, Ohtake, Fumiaki, Yoshida, Yukiko, Kasuga, Yusuke, Kondo, Takeshi, Yaguchi, Hiroaki, Suzuki, Masanobu, Ishida, Hiroki, Tanaka, Keiji, Hatakeyama, Shigetsugu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576197/
https://ncbi.nlm.nih.gov/pubmed/33082525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01328-y
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