A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets

The identification of true substrates of an E3 ligase is biologically important but biochemically difficult. In recent years, several techniques for identifying substrates have been developed, but these approaches cannot exclude indirect ubiquitination or have other limitations. Here we develop an E...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Watanabe, Masashi, Saeki, Yasushi, Takahashi, Hidehisa, Ohtake, Fumiaki, Yoshida, Yukiko, Kasuga, Yusuke, Kondo, Takeshi, Yaguchi, Hiroaki, Suzuki, Masanobu, Ishida, Hiroki, Tanaka, Keiji, Hatakeyama, Shigetsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7576197/
https://ncbi.nlm.nih.gov/pubmed/33082525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01328-y
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