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K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains
Different polyubiquitin chain linkages direct substrates toward distinct cellular pathways. K63-linked ubiquitylation is known to regulate proteasome-independent events such as signal transduction, but its function in the context of heterogeneous ubiquitin chains remains unclear. Here, we report tha...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5816176/ https://ncbi.nlm.nih.gov/pubmed/29378950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716673115 |
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