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Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

The melanoma-associated antigen family A (MAGEA) antigens are expressed in a wide variety of malignant tumors but not in adult somatic cells, rendering them attractive targets for cancer immunotherapy. Here we show that a number of cancer-associated MAGEA mutants that undergo proteasome-dependent de...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Tsang, Yiu Huen, Wang, Yumeng, Kong, Kathleen, Grzeskowiak, Caitlin, Zagorodna, Oksana, Dogruluk, Turgut, Lu, Hengyu, Villafane, Nicole, Bhavana, Venkata Hemanjani, Moreno, Daniela, Elsea, Sarah H, Liang, Han, Mills, Gordon B, Scott, Kenneth L
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164953/
https://ncbi.nlm.nih.gov/pubmed/32270762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48963
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