A comparative study of small molecules targeting eIF4A

The PI3K/Akt/mTOR kinase pathway is extensively deregulated in human cancers. One critical node under regulation of this signaling axis is eukaryotic initiation factor (eIF) 4F, a complex involved in the control of translation initiation rates. eIF4F-dependent addictions arise during tumor initiatio...

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Publicat a:RNA
Autors principals: Naineni, Sai Kiran, Itoua Maïga, Rayelle, Cencic, Regina, Putnam, Andrea A., Amador, Luis A., Rodriguez, Abimael D., Jankowsky, Eckhard, Pelletier, Jerry
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
Matèries:
Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161356/
https://ncbi.nlm.nih.gov/pubmed/32014999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.072884.119
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