Tracing MYC Expression for Small Molecule Discovery

Our inability to effectively “drug” targets such as MYC for therapeutic purposes requires the development of new approaches. We report on the implementation of a phenotype-based assay for monitoring MYC expression in multiple myeloma cells. The open reading frame (ORF) encoding an unstable variant o...

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Publicado en:Cell Chem Biol
Main Authors: Steinberger, Jutta, Robert, Francis, Hallé, Maxime, Williams, David E., Cencic, Regina, Sawhney, Neha, Pelletier, Dylan, Williams, Philip, Igarashi, Yasuhiro, Porco, John A., Rodriguez, Abimael D., Kopp, Brigitte, Bachmann, Brian, Andersen, Raymond J., Pelletier, Jerry
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525070/
https://ncbi.nlm.nih.gov/pubmed/30880156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.02.007
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