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Translation Inhibition by Rocaglates is Independent of eIF4E Phosphorylation Status
Rocaglates are natural products that inhibit protein synthesis in eukaryotes and exhibit anti-neoplastic activity. In vitro biochemical assays, affinity chromatography experiments coupled with mass spectrometry analysis, and in vivo genetic screens have identified eukaryotic initiation factor (eIF)...
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| Publicado no: | Mol Cancer Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707080/ https://ncbi.nlm.nih.gov/pubmed/26586722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0409 |
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