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Blocking UV-Induced eIF2α Phosphorylation with Small Molecule Inhibitors of GCN2
The eIF2α kinase general control non-depressible 2 integrates translation initiation rates to amino acid availability. General control non-depressible 2 also regulates translation initiation during synaptic plasticity and GCN2(−/−) mice show improved memory compared with wild-type mice with a reduce...
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| Udgivet i: | Chem Biol Drug Des |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221234/ https://ncbi.nlm.nih.gov/pubmed/19519745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2009.00827.x |
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