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GCN2 phosphorylation of eIF2α activates NF-κB in response to UV irradiation

In response to UV irradiation, mammalian cells elicit a gene expression programme designed to repair damage and control cell proliferation and apoptosis. Important members of this stress response include the NF-κB (nuclear factor-κB) family. However, the mechanisms by which UV irradiation activates...

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Autors principals: Jiang, Hao-Yuan, Wek, Ronald C.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134707/
https://ncbi.nlm.nih.gov/pubmed/15355306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041164
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