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Human keratinocyte differentiation requires translational control by the eIF2α kinase GCN2

Appropriate and sequential differentiation of keratinocytes is essential for all functions of the human epidermis. While transcriptional regulation has proven to be important for keratinocyte differentiation, little is known about the role of translational control. A key mechanism for modulating tra...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Collier, Ann E., Wek, Ronald C., Spandau, Dan F
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873978/
https://ncbi.nlm.nih.gov/pubmed/28528168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.04.029
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