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Human keratinocyte differentiation requires translational control by the eIF2α kinase GCN2

Appropriate and sequential differentiation of keratinocytes is essential for all functions of the human epidermis. While transcriptional regulation has proven to be important for keratinocyte differentiation, little is known about the role of translational control. A key mechanism for modulating tra...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Collier, Ann E., Wek, Ronald C., Spandau, Dan F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873978/
https://ncbi.nlm.nih.gov/pubmed/28528168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2017.04.029
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