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Role of eIF2α Kinases in Translational Control and Adaptation to Cellular Stress

A central mechanism regulating translation initiation in response to environmental stress involves phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF2α). Phosphorylation of eIF2α causes inhibition of global translation, which conserves energy and facilitates reprogramming of gen...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Biol
Autor principal: Wek, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6028073/
https://ncbi.nlm.nih.gov/pubmed/29440070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032870
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