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Role of eIF2α Kinases in Translational Control and Adaptation to Cellular Stress
A central mechanism regulating translation initiation in response to environmental stress involves phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF2α). Phosphorylation of eIF2α causes inhibition of global translation, which conserves energy and facilitates reprogramming of gen...
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| Published in: | Cold Spring Harb Perspect Biol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cold Spring Harbor Laboratory Press
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6028073/ https://ncbi.nlm.nih.gov/pubmed/29440070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a032870 |
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