Structure and Dynamics of Adrenomedullin Receptors AM(1) and AM(2) Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins

[Image: see text] Adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) receptors are critically important for metabolism, vascular tone, and inflammatory response. AM receptors are also required for normal lymphatic and blood vascular development and angiogenesis. They play a pivotal role...

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Bibliografski detalji
Izdano u:ACS Pharmacol Transl Sci
Glavni autori: Liang, Yi-Lynn, Belousoff, Matthew J., Fletcher, Madeleine M., Zhang, Xin, Khoshouei, Maryam, Deganutti, Giuseppe, Koole, Cassandra, Furness, Sebastian G. B., Miller, Laurence J., Hay, Debbie L., Christopoulos, Arthur, Reynolds, Christopher A., Danev, Radostin, Wootten, Denise, Sexton, Patrick M.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2020
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155201/
https://ncbi.nlm.nih.gov/pubmed/32296767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00080
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