Structure and Dynamics of Adrenomedullin Receptors AM(1) and AM(2) Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins

[Image: see text] Adrenomedullin (AM) and calcitonin gene-related peptide (CGRP) receptors are critically important for metabolism, vascular tone, and inflammatory response. AM receptors are also required for normal lymphatic and blood vascular development and angiogenesis. They play a pivotal role...

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Publicado en:ACS Pharmacol Transl Sci
Main Authors: Liang, Yi-Lynn, Belousoff, Matthew J., Fletcher, Madeleine M., Zhang, Xin, Khoshouei, Maryam, Deganutti, Giuseppe, Koole, Cassandra, Furness, Sebastian G. B., Miller, Laurence J., Hay, Debbie L., Christopoulos, Arthur, Reynolds, Christopher A., Danev, Radostin, Wootten, Denise, Sexton, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7155201/
https://ncbi.nlm.nih.gov/pubmed/32296767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsptsci.9b00080
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