Novel Genetic Variant of a Class B G Protein-Coupled Receptor Reveals a Role for Adrenomedullin in Human Fertility

Por Hay, Debbie L.
Publicado no ACS Pharmacol Transl Sci (2018)

Structure–function relationships of the N-terminus of receptor activity-modifying proteins

Por Qi, Tao, Hay, Debbie L
Publicado em 2010

Reply to comment on: A second trigeminal CGRP receptor: function and expression of the AMY1 receptor

Por Walker, Christopher S., Hay, Debbie L.
Publicado no Ann Clin Transl Neurol (2016)

Secretin family (Class B) G protein-coupled receptors – from molecular to clinical perspectives

Por Poyner, David R, Hay, Debbie L
Publicado em 2012

Amylin structure–function relationships and receptor pharmacology: implications for amylin mimetic drug development

Por Bower, Rebekah L, Hay, Debbie L
Publicado no Br J Pharmacol (2016)

RAMPs (Receptor-Activity Modifying Proteins): New Insights and Roles

Por Hay, Debbie L., Pioszak, Augen A.
Publicado no Annu Rev Pharmacol Toxicol (2015)

RAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors

Por Pioszak, Augen A., Hay, Debbie L.
Publicado no Adv Pharmacol (2020)

Calcitonin and Amylin Receptor Peptide Interaction Mechanisms: INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYI...

Por Lee, Sang-Min, Hay, Debbie L., Pioszak, Augen A.
Publicado no J Biol Chem (2016)

Calcitonin and amylin receptor peptide interaction mechanisms. INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYI...

Por Lee, Sang-Min, Hay, Debbie L., Pioszak, Augen A.
Publicado no J Biol Chem (2016)

Agonist bias and agonist‐dependent antagonism at corticotrophin releasing factor receptors

Por Tasma, Zoe, Wills, Peter, Hay, Debbie L., Walker, Christopher S.
Publicado no Pharmacol Res Perspect (2020)

Antagonism of CGRP Signaling by Rimegepant at Two Receptors

Por Pan, Kylie S., Siow, Andrew, Hay, Debbie L., Walker, Christopher S.
Publicado no Front Pharmacol (2020)

Characterization of the Structure of RAMP1 by Mutagenesis and Molecular Modeling

Por Simms, John, Hay, Debbie L., Wheatley, Mark, Poyner, David R.
Publicado em 2006

The pharmacology of Adrenomedullin 2/Intermedin

Por Hong, Yanguo, Hay, Debbie L, Quirion, Remi, Poyner, David R
Publicado em 2012

Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25

Por Hay, Debbie L, Garelja, Michael L, Poyner, David R, Walker, Christopher S
Publicado no Br J Pharmacol (2017)

Differential activation of G-proteins by μ-opioid receptor agonists

Por Saidak, Zuzana, Blake-Palmer, Katherine, Hay, Debbie L, Northup, John K, Glass, Michelle
Publicado em 2006

The third extracellular loop of the human calcitonin receptor-like receptor is crucial for the activation of adrenomedullin signalling

Por Kuwasako, Kenji, Hay, Debbie L, Nagata, Sayaka, Hikosaka, Tomomi, Kitamura, Kazuo, Kato, Johji
Publicado em 2012

Analysis of Amylin Consensus Sequences Suggests that Human Amylin is Not Optimized to Minimize Amyloid Formation and Provides Clues to Factors that Modulate Amyloidogenicity

Por Noh, Daeun, Bower, Rebekah L, Hay, Debbie L, Zhyvoloup, Alexander, Raleigh, Daniel P
Publicado no ACS Chem Biol (2020)

Structure–activity relationships for α-calcitonin gene-related peptide

Por Watkins, Harriet A, Rathbone, Dan L, Barwell, James, Hay, Debbie L, Poyner, David R
Publicado em 2013

CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured

Por Walker, Christopher S, Raddant, Ann C, Woolley, Michael J, Russo, Andrew F, Hay, Debbie L
Publicado no Cephalalgia (2017)

Probing the Mechanism of Receptor Activity–Modifying Protein Modulation of GPCR Ligand Selectivity through Rational Design of Potent Adrenomedullin and Calcitonin Gene-Related Pept...

Por Booe, Jason M., Warner, Margaret L., Roehrkasse, Amanda M., Hay, Debbie L., Pioszak, Augen A.
Publicado no Mol Pharmacol (2018)