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Agonist bias and agonist‐dependent antagonism at corticotrophin releasing factor receptors

The corticotropin‐releasing factor (CRF) receptors represent potential drug targets for the treatment of anxiety, stress, and other disorders. However, it is not known if endogenous CRF receptor agonists display biased signaling, how effective CRF receptor antagonists are at blocking different agoni...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Tasma, Zoe, Wills, Peter, Hay, Debbie L., Walker, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7290078/
https://ncbi.nlm.nih.gov/pubmed/32529807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.595
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