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Differential activation of G-proteins by μ-opioid receptor agonists
1. We investigated the ability of the activated μ-opioid receptor (MOR) to differentiate between myristoylated G(αi1) and G(αoA) type G(α) proteins, and the maximal activity of a range of synthetic and endogenous agonists to activate each G(α) protein. 2. Membranes from HEK293 cells stably expressin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1751342/ https://ncbi.nlm.nih.gov/pubmed/16415903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706661 |
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