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Differential activation of G-proteins by μ-opioid receptor agonists

1. We investigated the ability of the activated μ-opioid receptor (MOR) to differentiate between myristoylated G(αi1) and G(αoA) type G(α) proteins, and the maximal activity of a range of synthetic and endogenous agonists to activate each G(α) protein. 2. Membranes from HEK293 cells stably expressin...

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Bibliografiske detaljer
Main Authors: Saidak, Zuzana, Blake-Palmer, Katherine, Hay, Debbie L, Northup, John K, Glass, Michelle
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751342/
https://ncbi.nlm.nih.gov/pubmed/16415903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706661
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