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Absence of G-protein activation by μ-opioid receptor agonists in the spinal cord of μ-opioid receptor knockout mice
1. The ability of μ-opioid receptor agonists to activate G-proteins in the spinal cord of μ-opioid receptor knockout mice was examined by monitoring the binding to membranes of the non-hydrolyzable analogue of GTP, guanosine-5′-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS). 2. In the receptor binding...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565830/ https://ncbi.nlm.nih.gov/pubmed/10077238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702330 |
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