Involvement of Spinal Protein Kinase Cγ in the Attenuation of Opioid μ-Receptor-Mediated G-Protein Activation after Chronic Intrathecal Administration of [d-Ala(2),N-MePhe(4),Gly-Ol(5)]Enkephalin

The present study was designed to investigate the role of a protein kinase C (PKC) isoform in the uncoupling of the μ-opioid receptor from G-proteins after repeated intrathecal injection of a selective μ-receptor agonist, [d-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO), in the spinal cord of mice....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Narita, Minoru, Mizoguchi, Hirokazu, Narita, Michiko, Nagase, Hiroshi, Suzuki, Tsutomu, Tseng, Leon F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2001
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ARTICLE
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762716/
https://ncbi.nlm.nih.gov/pubmed/11356858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-11-03715.2001
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