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Comparing analgesia and μ-opioid receptor internalization produced by intrathecal enkephalin: requirement for peptidase inhibition

Opioid receptors in the spinal cord produce strong analgesia, but the mechanisms controlling their activation by endogenous opioids remain unclear. We have previously shown in spinal cord slices that peptidases preclude μ-opioid receptor (MOR) internalization by opioids. Our present goals were to in...

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Detalhes bibliográficos
Main Authors: Chen, Wenling, Song, Bingbing, Lao, Lijun, Pérez, Orlando A., Kim, Woojae, Marvizón, Juan Carlos G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083640/
https://ncbi.nlm.nih.gov/pubmed/17845806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2007.07.010
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