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Peptidases Prevent μ-Opioid Receptor Internalization in Dorsal Horn Neurons by Endogenously Released Opioids

To evaluate the effect of peptidases on μ-opioid receptor (MOR) activation by endogenous opioids, we measured MOR-1 internalization in rat spinal cord slices. A mixture of inhibitors of aminopeptidases (amastatin), dipeptidyl carboxypeptidase (captopril), and neutral endopeptidase (phosphoramidon) d...

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Detalhes bibliográficos
Main Authors: Song, Bingbing, Marvizón, Juan Carlos G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464295/
https://ncbi.nlm.nih.gov/pubmed/12629189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-05-01847.2003
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