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Ability of veratridine and high potassium to produce μ-opioid receptor internalization by evoking the release of opioid peptides in the rat spinal cord
Veratridine and high K(+) evoked opioid release in rat spinal cord slices, measured by μ-opioid receptor (MOR) internalization. Veratridine elicited up to 75% MOR internalization with an atypical concentration-response: its effect appeared abruptly from 5 μM to 10 μM, and declined thereafter to disa...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2410100/ https://ncbi.nlm.nih.gov/pubmed/18377995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2008.01.032 |
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