Genetic variability of the μ-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women

Labor initiates one of the most intensely painful episodes in a woman’s life. Opioids are used to provide analgesia with substantial interindividual variability in efficacy. μ-Opioid receptor (μOR, OPRM1) genetic variants may explain differences in response to opioid analgesia. We hypothesized that...

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Bibliographic Details
Main Authors: Landau, Ruth, Kern, Christian, Columb, Malachy O., Smiley, Richard M., Blouin, Jean-Louis
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669083/
https://ncbi.nlm.nih.gov/pubmed/18403122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2008.02.023
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