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The effect of pretreatment with a δ(2)-opioid receptor antisense oligodeoxynucleotide on the recovery from acute antinociceptive tolerance to δ(2)-opioid receptor agonist in the mouse spinal cord

1. An intrathecal (i.t.) injection of a selective δ(2)-opioid receptor agonist, [D-Ala(2)]deltorphin II, produced an acute antinociceptive tolerance to the antinociceptive effect of a subsequent i.t. challenge of [D-Ala(2)]deltorphin II. This acute tolerance lasted 3 to 9 h and completely subsided b...

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Detalhes bibliográficos
Main Authors: Narita, Minoru, Mizoguchi, Hirokazu, Kampine, John P, Tseng, Leon F
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564504/
https://ncbi.nlm.nih.gov/pubmed/9051295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0700944
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