Antibodies and antisense oligodeoxynucleotides to μ-opioid receptors, selectively block the effects of μ-opioid agonists on intestinal transit and permeability in mice

1. We have studied the effects of μ and δ opioids on intestinal function (permeability, PER; gastrointestinal transit, GIT), and their antagonism after the intracerebroventricular (i.c.v.) administration of specific antibodies (ABs) or antisense oligodeoxynucleotides (ODN) to μ-receptors (OR). Centr...

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Detalhes bibliográficos
Main Authors: Pol, Olga, Valle, Lluís, Sánchez-Blázquez, Pilar, Garzón, Javier, Puig, Margarita M
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1566040/
https://ncbi.nlm.nih.gov/pubmed/10385239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702570
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