Routine sub-2.5 Å cryo-EM structure determination of GPCRs

Cryo-electron microscopy (cryo-EM) of small membrane proteins, such as G protein-coupled receptors (GPCRs), remains challenging. Pushing the performance boundaries of the technique requires quantitative knowledge about the contribution of multiple factors. Here, we present an in-depth analysis and o...

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Pubblicato in:Nat Commun
Autori principali: Danev, Radostin, Belousoff, Matthew, Liang, Yi-Lynn, Zhang, Xin, Eisenstein, Fabian, Wootten, Denise, Sexton, Patrick M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8282782/
https://ncbi.nlm.nih.gov/pubmed/34267200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24650-3
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