Structure and dynamics of the active Gs-coupled human secretin receptor

The class B secretin GPCR (SecR) has broad physiological effects, with target potential for treatment of metabolic and cardiovascular disease. Molecular understanding of SecR binding and activation is important for its therapeutic exploitation. We combined cryo-electron microscopy, molecular dynamic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Dong, Maoqing, Deganutti, Giuseppe, Piper, Sarah J., Liang, Yi-Lynn, Khoshouei, Maryam, Belousoff, Matthew J., Harikumar, Kaleeckal G., Reynolds, Christopher A., Glukhova, Alisa, Furness, Sebastian G. B., Christopoulos, Arthur, Danev, Radostin, Wootten, Denise, Sexton, Patrick M., Miller, Laurence J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435274/
https://ncbi.nlm.nih.gov/pubmed/32811827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17791-4
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados