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ARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection

The Cullin-RING E3 ligase (CRL) family is commonly hijacked by pathogens to redirect the host ubiquitin proteasome machinery to specific targets. During HIV infection, CRL5 is hijacked by HIV Vif to target viral restriction factors of the APOBEC3 family for ubiquitination and degradation. Here, usin...

詳細記述

保存先:
書誌詳細
出版年:Cell Host Microbe
主要な著者: Hüttenhain, Ruth, Xu, Jiewei, Burton, Lily A., Gordon, David E., Hultquist, Judd F., Johnson, Jeffrey R., Satkamp, Laura, Hiatt, Joseph, Rhee, David Y., Baek, Kheewoong, Crosby, David C., Frankel, Alan D., Marson, Alexander, Harper, J. Wade, Alpi, Arno F., Schulman, Brenda A., Gross, John D., Krogan, Nevan J.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7153695/
https://ncbi.nlm.nih.gov/pubmed/31253590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.05.008
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