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Correlating Drug-Target Residence Time and Post-Antibiotic Effect: Insight into Target Vulnerability
Target vulnerability correlates the level of drug-target engagement required to generate a pharmacological response. High vulnerability targets are those that require only a relatively small fraction of occupancy to achieve the desired pharmacological outcome, whereas low vulnerability targets requi...
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| Gepubliceerd in: | ACS Infect Dis |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7150629/ https://ncbi.nlm.nih.gov/pubmed/32011855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00484 |
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