Novel tau filament fold in corticobasal degeneration

Corticobasal degeneration (CBD) is a neurodegenerative tauopathy that is characterised by motor and cognitive disturbances (1–3). A higher frequency of the H1 haplotype of MAPT, the tau gene, is present in cases of CBD than in controls (4,5) and genome-wide association studies have identified additi...

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I publikationen:Nature
Huvudupphovsmän: Zhang, Wenjuan, Tarutani, Airi, Newell, Kathy L., Murzin, Alexey G., Matsubara, Tomoyasu, Falcon, Benjamin, Vidal, Ruben, Garringer, Holly J., Shi, Yang, Ikeuchi, Takeshi, Murayama, Shigeo, Ghetti, Bernardino, Hasegawa, Masato, Goedert, Michel, Scheres, Sjors H.W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7148158/
https://ncbi.nlm.nih.gov/pubmed/32050258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2043-0
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