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Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for the design of new therapeutics. In response, clinical-stage th...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Chandler, Peter G., Buckle, Ashley M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140400/
https://ncbi.nlm.nih.gov/pubmed/32143310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030610
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