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Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for the design of new therapeutics. In response, clinical-stage th...

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Dades bibliogràfiques
Publicat a:Cells
Autors principals: Chandler, Peter G., Buckle, Ashley M.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140400/
https://ncbi.nlm.nih.gov/pubmed/32143310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030610
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