Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for the design of new therapeutics. In response, clinical-stage th...

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Detalhes bibliográficos
Main Authors: Peter G. Chandler, Ashley M. Buckle
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-03-01
Colecção:Cells
Assuntos:
adnectin
biosensor
fibronectin
monobody
non-antibody scaffold
therapeutic
Acesso em linha:https://www.mdpi.com/2073-4409/9/3/610
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