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Development and Differentiation in Monobodies Based on the Fibronectin Type 3 Domain

As a non-antibody scaffold, monobodies based on the fibronectin type III (FN3) domain overcome antibody size and complexity while maintaining analogous binding loops. However, antibodies and their derivatives remain the gold standard for the design of new therapeutics. In response, clinical-stage th...

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Podrobná bibliografie
Vydáno v:Cells
Hlavní autoři: Chandler, Peter G., Buckle, Ashley M.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140400/
https://ncbi.nlm.nih.gov/pubmed/32143310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030610
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