Isolation and Characterization of a Monobody with a Fibronectin Domain III Scaffold That Specifically Binds EphA2

Monobodies are binding scaffold proteins originating from a human fibronectin domain III (Fn3) scaffold that can be easily engineered with specificity and affinity. Human EphA2 (hEphA2) is an early detection marker protein for various tumors including lung, breast, and colon cancer. In this study, w...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Park, Seung-Hwan, Park, Sukho, Kim, Dong-Yeon, Pyo, Ayoung, Kimura, Richard H., Sathirachinda, Ataya, Choy, Hyon E., Min, Jung-Joon, Gambhir, Sanjiv Sam, Hong, Yeongjin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503726/
https://ncbi.nlm.nih.gov/pubmed/26177208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132976
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