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Structural and dynamic properties that govern the stability of an engineered fibronectin type III domain
Consensus protein design is a rapid and reliable technique for the improvement of protein stability, which relies on the use of homologous protein sequences. To enhance the stability of a fibronectin type III (FN3) domain, consensus design was employed using an alignment of 2123 sequences. The resul...
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Publicado no: | Protein Eng Des Sel |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4330816/ https://ncbi.nlm.nih.gov/pubmed/25691761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzv002 |
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