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Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
Kallikrein 4 (KLK4) is a serine protease that is predominantly expressed in the prostate and is overexpressed in prostate cancer. As such, it has gained attention as an attractive target for prostate cancer therapeutics. Currently, only liganded structures of KLK4 exist in the Protein Data Bank. Unt...
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| Veröffentlicht in: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Union of Crystallography
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688662/ https://ncbi.nlm.nih.gov/pubmed/31397325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19009610 |
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