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Crystal structure of the inhibitor-free form of the serine protease kallikrein-4

Kallikrein 4 (KLK4) is a serine protease that is predominantly expressed in the prostate and is overexpressed in prostate cancer. As such, it has gained attention as an attractive target for prostate cancer therapeutics. Currently, only liganded structures of KLK4 exist in the Protein Data Bank. Unt...

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Detaylı Bibliyografya
Yayımlandı:Acta Crystallogr F Struct Biol Commun
Asıl Yazarlar: Riley, Blake T., Hoke, David E., McGowan, Sheena, Buckle, Ashley M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6688662/
https://ncbi.nlm.nih.gov/pubmed/31397325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X19009610
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